Search on: TEMPORAL RNA, SMALL 
Descriptors Found: 1
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Descriptor English:   MicroRNAs 
Descriptor Spanish:   MicroARNs 
Descriptor Portuguese:   MicroRNAs 
Synonyms English:   Micro RNA
MicroRNA
Primary MicroRNA
Primary miRNA
miRNAs
pre-miRNA
pri-miRNA
MicroRNA, Primary
RNA, Micro
Temporal RNA, Small
miRNA, Primary
pre miRNA
pri miRNA
miRNA
RNA, Small Temporal
Small Temporal RNA
stRNA  
Tree Number:   D13.150.650.319
D13.444.735.150.319
D13.444.735.790.552.500
Definition English:   Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. 
See Related English:   RNA, Small Interfering
 
History Note English:   2003; use MICRORNAS (NM) 2001-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37535 
Unique Identifier:   D035683 

Occurrence in VHL:
 

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